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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
DIAPH1
All Species:
16.36
Human Site:
Y914
Identified Species:
36
UniProt:
O60610
Number Species:
10
Phosphosite Substitution
Charge Score:
-0.2
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O60610
NP_001073280.1
1272
141347
Y914
L
S
E
L
K
D
E
Y
D
D
L
A
E
S
E
Chimpanzee
Pan troglodytes
XP_509808
1253
142880
Y837
L
S
Q
F
K
S
E
Y
S
N
L
C
E
P
E
Rhesus Macaque
Macaca mulatta
XP_001089232
1269
142127
Y921
L
S
E
L
K
D
E
Y
D
D
L
A
E
S
E
Dog
Lupus familis
XP_857344
981
113022
L673
R
P
R
L
S
A
I
L
F
K
L
Q
F
E
E
Cat
Felis silvestris
Mouse
Mus musculus
O08808
1255
139325
Y897
L
S
E
L
K
E
E
Y
D
D
L
A
E
S
E
Rat
Rattus norvegicus
NP_001100863
346
39403
C38
I
V
S
V
T
A
A
C
E
E
L
R
K
S
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
NP_989541
1253
139246
Y925
L
A
A
L
Q
D
E
Y
N
D
L
A
E
S
E
Frog
Xenopus laevis
Q6NTV6
1099
121463
K758
L
K
S
Y
Q
E
D
K
A
K
L
S
N
A
D
Zebra Danio
Brachydanio rerio
XP_683813
932
105075
K624
L
A
P
K
K
T
Y
K
P
D
S
I
M
K
R
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P48608
1091
123153
G744
L
Q
E
I
K
A
K
G
E
P
L
P
P
I
E
Honey Bee
Apis mellifera
XP_395654
1140
128906
F819
K
N
G
Q
A
F
G
F
E
I
S
F
L
T
K
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
34.5
91.8
43.2
N.A.
90.3
25.7
N.A.
N.A.
53
27.2
40.4
N.A.
36.7
39.5
N.A.
N.A.
Protein Similarity:
100
50
93.2
58.4
N.A.
93.4
26.3
N.A.
N.A.
68.4
46.4
53.7
N.A.
54.8
58
N.A.
N.A.
P-Site Identity:
100
53.3
100
20
N.A.
93.3
20
N.A.
N.A.
73.3
13.3
20
N.A.
33.3
0
N.A.
N.A.
P-Site Similarity:
100
66.6
100
20
N.A.
100
53.3
N.A.
N.A.
93.3
53.3
26.6
N.A.
53.3
33.3
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
19
10
0
10
28
10
0
10
0
0
37
0
10
0
% A
% Cys:
0
0
0
0
0
0
0
10
0
0
0
10
0
0
0
% C
% Asp:
0
0
0
0
0
28
10
0
28
46
0
0
0
0
10
% D
% Glu:
0
0
37
0
0
19
46
0
28
10
0
0
46
10
73
% E
% Phe:
0
0
0
10
0
10
0
10
10
0
0
10
10
0
0
% F
% Gly:
0
0
10
0
0
0
10
10
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
10
0
0
10
0
0
10
0
0
10
0
10
0
10
0
% I
% Lys:
10
10
0
10
55
0
10
19
0
19
0
0
10
10
10
% K
% Leu:
73
0
0
46
0
0
0
10
0
0
82
0
10
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
10
0
0
% M
% Asn:
0
10
0
0
0
0
0
0
10
10
0
0
10
0
0
% N
% Pro:
0
10
10
0
0
0
0
0
10
10
0
10
10
10
0
% P
% Gln:
0
10
10
10
19
0
0
0
0
0
0
10
0
0
0
% Q
% Arg:
10
0
10
0
0
0
0
0
0
0
0
10
0
0
10
% R
% Ser:
0
37
19
0
10
10
0
0
10
0
19
10
0
46
0
% S
% Thr:
0
0
0
0
10
10
0
0
0
0
0
0
0
10
0
% T
% Val:
0
10
0
10
0
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
10
0
0
10
46
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _